William Ed McCullough (born October 1863; died June 1915) married 29 August 1886 in Clay County, Indiana to Samantha E. DeCamp (born October 1866; died December 1951). Ed McCullough was a school teacher.
Children of Ed & Samantha McCullough:
- Rachel Esther McCullough (born 27 January 1888 in Asherville, Clay County, Indiana; died July 1958) - married 9 June 1907 in Clay County to David Wilson Stein (born 11 October 1886 in Scotland; died May 1959).
- Charles Grandison McCullough (born 19 October 1893; died 1949; buried in Poland Chapel Cemetery, Poland, Clay County, Indiana) - married 5 October 1918 in Vigo County, Indiana to Anna May Keiser (born 17 June 1898; died 1989; buried in Poland Chapel Cemetery).
- Lela/Leona McCullough (born April 1900; died after 1940) - Lela was a teacher in Terre Haute. She is listed as divorced in the 1940 census.
- Ruth A. McCullough (born 15 August 1906 in Knightsville, Clay County; died January 1995) - married 14 June 1931 in Parke County, Indiana to Culver W. Krantz (born 4 March 1906 in Highland, Illinois; died June 2000). Ruth was a teacher in Terre Haute.